Pregabalin: CAS # 148553-50-8 - RM100.00

Date Posted: 14-01-2023 11:12 AM    Location: 中国, Wuhan, Negeri Sembilan    Posted by: sunny    Views: 84 times
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Pregabaline, chemical name (s) - 3-aminomethyl-5-methylcaproic acid, molecular formula c8h17no2, is an antiepileptic drug, which is mainly used to treat postherpetic neuralgia clinically. Physicochemical properties
Appearance and properties: white or almost white crystalline powder
Density: 0.997 g / cm3
Melting point: 194-196 º C
Boiling point: 274 º C at 760 mmHg
Flash point: 119.5 º C
Refractive index: 1.464
Steam pressure: 0.00153mmhg at 25 ° C [1]
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For the treatment of peripheral neuralgia, or adjuvant treatment of partial seizures
Pregabaline γ- Aminobutyric acid (GABA) analogues, similar in structure and function to gabapentin, have antiepileptic, analgesic and anti anxiety activities. The antiepileptic mechanism of pregabaline is not clear. In laboratory studies, pregabaline has anticonvulsant activity against various epilepsy models; The activity spectrum of animal model was similar to that of gabapentin, but the activity of pregabaline was 3 ~ 10 times that of gabapentin